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Understanding Neuromodulation: Techniques and Applications in Modern Neurology

Title: Understanding Neuromodulation: Techniques and Applications in Modern Neurology

In the realm of innovative and unique technologies, Quantum Re-Generation stands out as a groundbreaking solution for treating pain and acting at the muscular level with decontraction action. This is achieved through the emission of high-tension depolarizing microcurrents.

This therapeutic action targets acute chronic and post-traumatic pain, as well as exhibiting anti-inflammatory and decontraction properties. The mechanism of action is through the Gate Control Theory, allowing for the inhibition of nociceptive afferent transmission that occurs through small-diameter fibers. This is accomplished through the use of pulsed microcurrents with a time period of one millionth of a second per impulse, acting on muscular tissue and exhibiting decontraction effects while increasing tissue oxygenation.

The technique applies a procedure of electro-analgesia and neuro-modulation. In general, the ultimate goal of any analgesia technique is always to inhibit the transmission of the pain impulse using an electric stimulus. The Re-Generation device features interchangeable tip attachments for treating small, localized areas such as the temporomandibular joint or extended areas like the treatment of peripheral nerve canal syndromes such as the Sciatic Nerve.

The Re-Generation acts through the use of depolarizing high-tension microcurrents, working on the inhibition of pain by blocking the transmission of nociceptors and acting on cellular regeneration. It is an electroanalgesia technique. External electrodes act on C-fibers (specialized neurons that transmit pain sensations slowly and deeply) to provide a ‘counter-information’.

The analgesic effect is immediate. Similarly, as chronic pain remodels neural circuits and creates ‘vicious circles’ that amplify suffering, repeated application of this therapy with a complete cycle of multiple sessions can remodel these altered sensory circuits, allowing for a reduction in hyper-sensitivity to pain.

To date, the Re-Generation has been widely tested on patients with various painful musculoskeletal symptoms, neuropathic pain, and even oncological pain in different pathologies:

The Quantum Re-Generation has proven extremely useful after just the first application on patients with sub-acromial conflict syndrome and pain in the supraspinatus tendon and rotator cuff tendinitis.

It has shown effective in inhibiting the pain caused by plantar fasciitis generated by calcaneal spurs.

It has been tested with positive results on patients with degenerative joint arthrosis with pain and functional limitation, treating all lower back, cervical, dorsal, and sacro-coccygeal pain.

It has shown very positive results on rheumatoid arthritis and arthrosis of the hand, showing a clear reduction in pain with an increase in hand function.

Patients with chronic pain present for more than six months and acute pain from recent trauma, such as distortive ankle trauma, have shown positive results. Positive results have also been obtained in the treatment of issues related to ligamentous and muscular problems such as iliotibial band syndrome with pain and limitation of mobility.

The technology has been tested on patients with temporomandibular joint dysfunction, pain at the level of the masticatory muscles due to Bruxism and pain at the joint. In this type of patient, a clear reduction in pain and a reduction in muscle hypertonia that generated Bruxism, both concentric and eccentric, have been observed.

The device has been used in a case of neurological rigidity due to Motor Neuron Disease, Sclerosis Laterale Amiotrofica. The patient showed a clear reduction in muscle hypertonia with a significant improvement in walking.

The Re-Generation has been used as an antalgic therapy in the management of oncological pain not responsive to opioids, showing clear reductions in perceived pain levels. The treatment has been focused on painful bone metastases after Radiotherapy. The device has also been used in the veterinary field. Specifically, dogs with degenerative joint arthrosis in their limbs have been treated. Already from the first treatment, the dog has improved its global mobility, index of a clear reduction in pain. Improvement in joint excursion and walking on all four limbs with complete weight distribution has been observed.

The device has been well tolerated and accepted by all patients. No side effects of any kind have been observed, and all treated patients have shown a significant reduction in pain.